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A group of international scientists is sounding a global alarm, warning that population growth, climate change and environmental destruction are pushing Earth toward calamitous — and irreversible — biological changes.

In a paper published in Thursday’s edition of the journal Nature, 22 researchers from a variety of fields liken the human impact to global events eons ago that caused mass extinctions, permanently altering Earth’s biosphere.

“Humans are now forcing another such transition, with the potential to transform Earth rapidly and irreversibly into a state unknown in human experience,” wrote the authors, who are from the U.S., Europe, Canada and South America.

If current trends continue — exploding global population, rapidly rising temperatures and the clearance of more than 40% of Earth’s surface for urban development or agriculture — the planet could reach a tipping point, they say.

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